From Knowledge to Action: Outcomes of the 2025 Large Language Model (LLM) Hackathon for Applications in Materials Science and Chemistry

Large language models (LLMs) are rapidly changing how researchers in materials science and chemistry discover, organize, and act on scientific knowledge. This paper analyzes a broad set of community-developed LLM applications in an effort to identify emerging patterns in how these systems can be used across the scientific research lifecycle. We organize the projects into two complementary categories: Knowledge Infrastructure, systems that structure, retrieve, synthesize, and validate scientific information; and Action Systems, systems that execute, coordinate, or automate scientific work across computational and experimental environments. The submissions reveal a shift from single-purpose LLM tools toward integrated, multi-agent workflows that combine retrieval, reasoning, tool use, and domain-specific validation. Prominent themes include retrieval-augmented generation as grounding infrastructure, persistent structured knowledge representations, multimodal and multilingual scientific inputs, and early progress toward laboratory-integrated closed-loop systems. Together, these results suggest that LLMs are evolving from general-purpose assistants into composable infrastructure for scientific reasoning and action. This work provides a community snapshot of that transition and a practical taxonomy for understanding emerging LLM-enabled workflows in materials science and chemistry.

MiMo-V2-Flash Technical Report

We present MiMo-V2-Flash, a Mixture-of-Experts (MoE) model with 309B total parameters and 15B active parameters, designed for fast, strong reasoning and agentic capabilities. MiMo-V2-Flash adopts a hybrid attention architecture that interleaves Sliding Window Attention (SWA) with global attention, with a 128-token sliding window under a 5:1 hybrid ratio. The model is pre-trained on 27 trillion tokens with Multi-Token Prediction (MTP), employing a native 32k context length and subsequently extended to 256k. To efficiently scale post-training compute, MiMo-V2-Flash introduces a novel Multi-Teacher On-Policy Distillation (MOPD) paradigm. In this framework, domain-specialized teachers (e.g., trained via large-scale reinforcement learning) provide dense and token-level reward, enabling the student model to perfectly master teacher expertise. MiMo-V2-Flash rivals top-tier open-weight models such as DeepSeek-V3.2 and Kimi-K2, despite using only 1/2 and 1/3 of their total parameters, respectively. During inference, by repurposing MTP as a draft model for speculative decoding, MiMo-V2-Flash achieves up to 3.6 acceptance length and 2.6x decoding speedup with three MTP layers. We open-source both the model weights and the three-layer MTP weights to foster open research and community collaboration.

MiMo-Audio: Audio Language Models are Few-Shot Learners

Existing audio language models typically rely on task-specific fine-tuning to accomplish particular audio tasks. In contrast, humans are able to generalize to new audio tasks with only a few examples or simple instructions. GPT-3 has shown that scaling next-token prediction pretraining enables strong generalization capabilities in text, and we believe this paradigm is equally applicable to the audio domain. By scaling MiMo-Audio's pretraining data to over one hundred million of hours, we observe the emergence of few-shot learning capabilities across a diverse set of audio tasks. We develop a systematic evaluation of these capabilities and find that MiMo-Audio-7B-Base achieves SOTA performance on both speech intelligence and audio understanding benchmarks among open-source models. Beyond standard metrics, MiMo-Audio-7B-Base generalizes to tasks absent from its training data, such as voice conversion, style transfer, and speech editing. MiMo-Audio-7B-Base also demonstrates powerful speech continuation capabilities, capable of generating highly realistic talk shows, recitations, livestreaming and debates. At the post-training stage, we curate a diverse instruction-tuning corpus and introduce thinking mechanisms into both audio understanding and generation. MiMo-Audio-7B-Instruct achieves open-source SOTA on audio understanding benchmarks (MMSU, MMAU, MMAR, MMAU-Pro), spoken dialogue benchmarks (Big Bench Audio, MultiChallenge Audio) and instruct-TTS evaluations, approaching or surpassing closed-source models. Model checkpoints and full evaluation suite are available at https://github.com/XiaomiMiMo/MiMo-Audio.

GroundingME: Exposing the Visual Grounding Gap in MLLMs through Multi-Dimensional Evaluation

Visual grounding, localizing objects from natural language descriptions, represents a critical bridge between language and vision understanding. While multimodal large language models (MLLMs) achieve impressive scores on existing benchmarks, a fundamental question remains: can MLLMs truly ground language in vision with human-like sophistication, or are they merely pattern-matching on simplified datasets? Current benchmarks fail to capture real-world complexity where humans effortlessly navigate ambiguous references and recognize when grounding is impossible. To rigorously assess MLLMs' true capabilities, we introduce GroundingME, a benchmark that systematically challenges models across four critical dimensions: (1) Discriminative, distinguishing highly similar objects, (2) Spatial, understanding complex relational descriptions, (3) Limited, handling occlusions or tiny objects, and (4) Rejection, recognizing ungroundable queries. Through careful curation combining automated generation with human verification, we create 1,005 challenging examples mirroring real-world complexity. Evaluating 25 state-of-the-art MLLMs reveals a profound capability gap: the best model achieves only 45.1% accuracy, while most score 0% on rejection tasks, reflexively hallucinating objects rather than acknowledging their absence, raising critical safety concerns for deployment. We explore two strategies for improvements: (1) test-time scaling selects optimal response by thinking trajectory to improve complex grounding by up to 2.9%, and (2) data-mixture training teaches models to recognize ungroundable queries, boosting rejection accuracy from 0% to 27.9%. GroundingME thus serves as both a diagnostic tool revealing current limitations in MLLMs and a roadmap toward human-level visual grounding.

Lumina-mGPT 2.0: Stand-Alone AutoRegressive Image Modeling

We present Lumina-mGPT 2.0, a stand-alone, decoder-only autoregressive model that revisits and revitalizes the autoregressive paradigm for high-quality image generation and beyond. Unlike existing approaches that rely on pretrained components or hybrid architectures, Lumina-mGPT 2.0 is trained entirely from scratch, enabling unrestricted architectural design and licensing freedom. It achieves generation quality on par with state-of-the-art diffusion models such as DALL-E 3 and SANA, while preserving the inherent flexibility and compositionality of autoregressive modeling. Our unified tokenization scheme allows the model to seamlessly handle a wide spectrum of tasks-including subject-driven generation, image editing, controllable synthesis, and dense prediction-within a single generative framework. To further boost usability, we incorporate efficient decoding strategies like inference-time scaling and speculative Jacobi sampling to improve quality and speed, respectively. Extensive evaluations on standard text-to-image benchmarks (e.g., GenEval, DPG) demonstrate that Lumina-mGPT 2.0 not only matches but in some cases surpasses diffusion-based models. Moreover, we confirm its multi-task capabilities on the Graph200K benchmark, with the native Lumina-mGPT 2.0 performing exceptionally well. These results position Lumina-mGPT 2.0 as a strong, flexible foundation model for unified multimodal generation. We have released our training details, code, and models at https://github.com/Alpha-VLLM/Lumina-mGPT-2.0.

MiMo: Unlocking the Reasoning Potential of Language Model -- From Pretraining to Posttraining

We present MiMo-7B, a large language model born for reasoning tasks, with optimization across both pre-training and post-training stages. During pre-training, we enhance the data preprocessing pipeline and employ a three-stage data mixing strategy to strengthen the base model's reasoning potential. MiMo-7B-Base is pre-trained on 25 trillion tokens, with additional Multi-Token Prediction objective for enhanced performance and accelerated inference speed. During post-training, we curate a dataset of 130K verifiable mathematics and programming problems for reinforcement learning, integrating a test-difficulty-driven code-reward scheme to alleviate sparse-reward issues and employing strategic data resampling to stabilize training. Extensive evaluations show that MiMo-7B-Base possesses exceptional reasoning potential, outperforming even much larger 32B models. The final RL-tuned model, MiMo-7B-RL, achieves superior performance on mathematics, code and general reasoning tasks, surpassing the performance of OpenAI o1-mini. The model checkpoints are available at https://github.com/xiaomimimo/MiMo.

TimeChat-Online: 80% Visual Tokens are Naturally Redundant in Streaming Videos

The rapid growth of online video platforms, particularly live streaming services, has created an urgent need for real-time video understanding systems. These systems must process continuous video streams and respond to user queries instantaneously, presenting unique challenges for current Video Large Language Models (VideoLLMs). While existing VideoLLMs excel at processing complete videos, they face significant limitations in streaming scenarios due to their inability to handle dense, redundant frames efficiently. We introduce TimeChat-Online, a novel online VideoLLM that revolutionizes real-time video interaction. At its core lies our innovative Differential Token Drop (DTD) module, which addresses the fundamental challenge of visual redundancy in streaming videos. Drawing inspiration from human visual perception's Change Blindness phenomenon, DTD preserves meaningful temporal changes while filtering out static, redundant content between frames. Remarkably, our experiments demonstrate that DTD achieves an 82.8% reduction in video tokens while maintaining 98% performance on StreamingBench, revealing that over 80% of visual content in streaming videos is naturally redundant without requiring language guidance. To enable seamless real-time interaction, we present TimeChat-Online-139K, a comprehensive streaming video dataset featuring diverse interaction patterns including backward-tracing, current-perception, and future-responding scenarios. TimeChat-Online's unique Proactive Response capability, naturally achieved through continuous monitoring of video scene transitions via DTD, sets it apart from conventional approaches. Our extensive evaluation demonstrates TimeChat-Online's superior performance on streaming benchmarks (StreamingBench and OvOBench) and maintaining competitive results on long-form video tasks such as Video-MME and MLVU.

QAMA: Quantum annealing multi-head attention operator with classical deep learning framework

As large language models scale up, the conventional attention mechanism faces critical challenges of exponential growth in memory consumption and energy costs. Quantum annealing computing, with its inherent advantages in computational efficiency and low energy consumption, offers an innovative direction for constructing novel deep learning architectures. This study proposes the first Quantum Annealing-based Multi-head Attention (QAMA) mechanism, achieving seamless compatibility with classical attention architectures through quadratic unconstrained binary optimization (QUBO) modeling of forward propagation and energy-based backpropagation. The method innovatively leverages the quantum bit interaction characteristics of Ising models to optimize the conventional $O(n^2)$ spatiotemporal complexity into linear resource consumption. Integrated with the optical computing advantages of coherent Ising machines (CIM), the system maintains millisecond-level real-time responsiveness while significantly reducing energy consumption. Our key contributions include: Theoretical proofs establish QAMA mathematical equivalence to classical attention mechanisms; Dual optimization of multi-head specificity and long-range information capture via QUBO constraints; Explicit gradient proofs for the Ising energy equation are utilized to implement gradient conduction as the only path in the computational graph as a layer; Proposed soft selection mechanism overcoming traditional binary attention limitations to approximate continuous weights. Experiments on QBoson CPQC quantum computer show QAMA achieves comparable accuracy to classical operators while reducing inference time to millisecond level and improving solution quality. This work pioneers architectural-level integration of quantum computing and deep learning, applicable to any attention-based model, driving paradigm innovation in AI foundational computing.

Every FLOP Counts: Scaling a 300B Mixture-of-Experts LING LLM without Premium GPUs

In this technical report, we tackle the challenges of training large-scale Mixture of Experts (MoE) models, focusing on overcoming cost inefficiency and resource limitations prevalent in such systems. To address these issues, we present two differently sized MoE large language models (LLMs), namely Ling-Lite and Ling-Plus (referred to as "Bailing" in Chinese, spelled B\v{a}il\'ing in Pinyin). Ling-Lite contains 16.8 billion parameters with 2.75 billion activated parameters, while Ling-Plus boasts 290 billion parameters with 28.8 billion activated parameters. Both models exhibit comparable performance to leading industry benchmarks. This report offers actionable insights to improve the efficiency and accessibility of AI development in resource-constrained settings, promoting more scalable and sustainable technologies. Specifically, to reduce training costs for large-scale MoE models, we propose innovative methods for (1) optimization of model architecture and training processes, (2) refinement of training anomaly handling, and (3) enhancement of model evaluation efficiency. Additionally, leveraging high-quality data generated from knowledge graphs, our models demonstrate superior capabilities in tool use compared to other models. Ultimately, our experimental findings demonstrate that a 300B MoE LLM can be effectively trained on lower-performance devices while achieving comparable performance to models of a similar scale, including dense and MoE models. Compared to high-performance devices, utilizing a lower-specification hardware system during the pre-training phase demonstrates significant cost savings, reducing computing costs by approximately 20%. The models can be accessed at https://huggingface.co/inclusionAI.

Lumina-Video: Efficient and Flexible Video Generation with Multi-scale Next-DiT

Recent advancements have established Diffusion Transformers (DiTs) as a dominant framework in generative modeling. Building on this success, Lumina-Next achieves exceptional performance in the generation of photorealistic images with Next-DiT. However, its potential for video generation remains largely untapped, with significant challenges in modeling the spatiotemporal complexity inherent to video data. To address this, we introduce Lumina-Video, a framework that leverages the strengths of Next-DiT while introducing tailored solutions for video synthesis. Lumina-Video incorporates a Multi-scale Next-DiT architecture, which jointly learns multiple patchifications to enhance both efficiency and flexibility. By incorporating the motion score as an explicit condition, Lumina-Video also enables direct control of generated videos' dynamic degree. Combined with a progressive training scheme with increasingly higher resolution and FPS, and a multi-source training scheme with mixed natural and synthetic data, Lumina-Video achieves remarkable aesthetic quality and motion smoothness at high training and inference efficiency. We additionally propose Lumina-V2A, a video-to-audio model based on Next-DiT, to create synchronized sounds for generated videos. Codes are released at https://www.github.com/Alpha-VLLM/Lumina-Video.